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PEOPLE - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/581c906f-5ca3-4764-8d23-72dd578c2c55/Anna.jpg Home - PEOPLE - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/117294fb-1976-4c8d-955b-13cd9d748510/Anna.jpg Home - PEOPLE - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/4d4e2358-b7f1-4042-821f-99d0df9e3e78/Falk.jpg Home - PEOPLE https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/bf99c406-37db-4700-ba25-e62d5aa7904d/Falk.jpg Home - PEOPLE https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/d9efa05e-e1b3-4850-9941-70e0658cf0b0/Falk.jpg Home - PEOPLE - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/2e6043d1-dbc3-4da2-82e3-bbc011c2ff7e/Falk.jpg Home - 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PEOPLE https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/1570447714573-CWMJ7PDFK272N05AS6DW/IMG_20190927_214947.jpg Home - PEOPLE https://www.bpi-oxford.com/home/research monthly 0.5 2024-11-03 https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/2e803810-4d08-4741-a10f-bf020f3f813e/Research02.jpg Home - RESEARCH https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/eb420b0c-cde9-4d70-a896-d81775d3316b/research04.jpg Home - RESEARCH https://www.bpi-oxford.com/home/publications monthly 0.5 2026-01-28 https://www.bpi-oxford.com/home/protocols monthly 0.5 2024-11-03 https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/7cb9ddb1-04d1-40a4-92fa-e370a6252085/Tech11.jpg Home - TECHNOLOGY DEVELOPMENT - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/1553162381444-CLNFE59NUVY4N5Y8NAVH/TIRF-SIM_2colour Home - TECHNOLOGY DEVELOPMENT Figure shows a comparison between conventional TIRF and eTIRF-SIM modalities. HT1080 cell cultured on a gelatin-coated cover glass ( MT1-MMP red, Beta 1 Integrin blue, F-actin green) sample courtesy Valentina GIfford. https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/1553441731801-7TCD4T8O23H87Y1DQFTK/Screenshot+from+2019-03-24+15-33-35.png Home - TECHNOLOGY DEVELOPMENT Schematic of the experiment principle. (Left) sFCS data are recorded by scanning the laser (green dots) along a micrometer line in the membrane (lipids with red headgroups and gray tails), thereby creating (through temporal correlations) FCS data (decaying curves G(τ) from red to blue against correlation time τ) for each pixel along the line (space). (Right) All FCS data are fitted to obtain values of transit times through the observation spot, in which histograms (blue, probability distributions; right, cumulative; top right, logarithmic values; bottom right, linear representation) are fitted by the LogNorm (red line), with weighted residuals in the respective bottom panels. https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/1521241686566-M4Z66EJHSZMDSVWL2TRH/Figure%2Btaken%2Bfrom%2BFritzsche%2Bet%2Bal%2C%2BNature%2BProtocols%2B2015.png Home - TECHNOLOGY DEVELOPMENT Figure taken from Fritzsche et al, Nature Protocols 2015. https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/1521242051750-J3LDKGA4CGPW2N5BCQ03/STFM.png Home - TECHNOLOGY DEVELOPMENT Figure taken from Colin-York et al, Nature Protocols 2017. https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/5a3a9feb-d7e2-4182-9100-baa3455a9157/TFM.jfif Home - TECHNOLOGY DEVELOPMENT - Make it stand out Figure taken from Colin-York, Nature Device & Materials Engineering, 2021. https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/1577656483640-62OI2DC7S8MIROTMFPVY/TOC_figure_AFM-FRAP_Small_1_800DPI.png.png Home - TECHNOLOGY DEVELOPMENT AFM-FRAP setup quantifying the mechanoadaptation of the actin turnover rate upon constant force application in living cells. First application of this technical combination showed that cells respond to external force by decreasing their actin turnover yielding longer filaments. Figure taken from Skamrahl et al, Small 2019. https://www.bpi-oxford.com/home/2018/9/7/job-opportunities monthly 0.5 2024-11-02 https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/1536308312890-EU76L6K7E8H0IWF4W5GE/business-opportunity.jpg Home - JOB OPPORTUNITIES https://www.bpi-oxford.com/home/collaborators monthly 0.5 2023-03-09 https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/1521240623368-XKRET5HQPI1927BUVICL/Connected_World.jpg Home - SCIENTIFIC COLLABORATORS https://www.bpi-oxford.com/home/software monthly 0.5 2019-03-24 https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/1553444049366-87QMBZXXK0AN3BKYR7KB/srep16487-f1.jpg Home - SOFTWARE Figure taken from Fritzsche et al, Scientific Reports, 2015. Representative intensity profiles R(t) (upper panel) and their derivatives dR(t)/dt (lower panel); average over 200-650 individual T-cells (black circles: raw data, mangenta line: Savitzky–Golay interpolation for signaling T-cells, purple line: data of non-signaling cells). CalQuodetermines the characteristic times for the landing (grey shaded area) and signaling event (magenta shaded area) from the characteristic peaks in dR(t)/dt. Error bars representing s.d.m. https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/1553443694413-562D4O5P1U919GSDV5F0/41598_2017_5322_Fig1_HTML.jpg Home - SOFTWARE Figure taken from Lee AM & Colin-York et al, Scientific Reports 2017. Representative normalized Ca2+ based fluorescence intensity plot of a Jurkat T-cell upon landing on a 4D:MHC I functionalized coverslip with a subset of cells. Scale bar is 100 µm. https://www.bpi-oxford.com/home/contact monthly 0.5 2024-11-02 https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/0fde486b-8564-479d-ab3b-19c0b61bdb98/KIR.jpg Home - CONTACT https://images.squarespace-cdn.com/content/v1/5aabe152cc8fed04320dac67/b58191a8-4d43-45ef-9546-7a80761e313b/RFI02.jpg Home - CONTACT https://www.bpi-oxford.com/home/media monthly 0.5 2025-07-04